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Jianguo, Tao MD, Ph.D.
Attending and Clinical Professor
Pathology Hematopathology
Education:
Henan, Henan Medical University
Main Office:
434-924-2283,
UVA Health,
1215 Lee St,
Charlottesville, VA 22903 
Clinic Intersts:
hematopathology.
Certification: Board Certified in Pathology AP/CP, Hemapathology
Ph.D.: University of Miami, 1994
Research Interests: 1) functional genomics and biomarkers of lymphoma; including microRNA
expression profile in selected lymphoma subtypes (mantle cell lymphoma and viral-associated lymphomas) to determine possible involvement of microRNAs in the pathogenesis of non-Hodgkin lymphoma and their possible role in diagnosis, prognosis and therapeutic target discovery, 2) microenvironment regulation of molecular pathogenesis of lymphoma; his laboratory is studying the normal development of germinal center B cells.His team aims to determine microenvironment regulation of normal and abnormal transcriptional factors and miRNAs involved in B-cell differentiation, activation and lymphomagenesis, 3) Microenvironment regulation of drug resistance of lymphoma. The team’s recent studies have shown that adhesion of lymphoma cells to bone marrow stromal cells significantly increases cellular resistance to a variety of cytotoxic drugs and induces cell cycle arrest.
They have extended this research to determine the role of the interaction between lymph node stromal cell and lymphoma cells as well as miRNAs in response to therapy and to further elucidate the molecular mechanisms by which stroma regulates lymphoma cell survival.
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