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Zhao, Xianfeng Frank, MD, Ph.D.
Attending and Clinical Professor
Pathology |
Hematopathology |
Molecular Genetic Pathology
Clinic:
University of Arizona College of Medicine Phoenix
550 E. Van Buren St,
Phoenix, AZ 85004 US (Get Direction)
Phone: 410-328-5555
Education:
Graduated from: Shandong, Shandong University College of Medicine
Residency: SUNY Buffalo
Fellowship: Penn Medicine
Clinical Interests:
hematopathology.
Languge:
Besides English, Dr. Zhao can speak Mandarin as well.
Ph.D.: University of Western Ontario
Research Interests:
Dr. Zhao has been interested in the discovery of biomarkers for the diagnosis
and molecular targets for the treatment of diffuse large B-cell lymphoma (DLBCL). Based on his
observation that RPS6KB1 and CDC2 genes were amplified in a subset of DLBCL, he and his coworkers
evaluated the activity of RPS6KB1 and CDC2 gene products in DLBCL and found that their activities
were responsible for the proliferation of lymphoma cells. Targeting their products inhibited the
proliferation and led to apoptosis of the lymphoma cells. In collaboration with numerous
physicians/scientists nationwide, he also investigated the molecular mechanism of lymphoma
development, particularly the crosstalk between the different signal transduction pathways of DLBCL.
Dr. Zhao recently became interested in HIV-related malignant lymphomas. He will continue to pursue
both independent and collaborative endeavors in discovering novel biomarkers and understanding the
molecular biology of hematologic malignancies.
Data Resources:
https://phoenixmed.arizona.edu/newsroom/news/college-names-chair-pathology
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